Description
Product Characteristics: For the quantitative determination of human uncharacterized protein C9orf72 (C9orf72) concentrations in serum, plasma, tissue homogenates, cell lysates.
Target Information: Expansion of a hexanucleotide repeat in non-coding sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778, 21944779). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]